Mekong Delta Tours, also known as the South-western region, is the region in southwestern Vietnam where the Mekong River approaches and empties into the sea through a network of distributaries. The Mekong delta region encompasses a large portion of southwestern Vietnam of over 40,500 square kilometres. The size of the area covered by water depends on the season. The region comprises 12 provinces: Long An, Đồng Tháp, Tiền Giang, An Giang, Bến Tre, Vĩnh Long, Trà Vinh, Hậu Giang, Kiên Giang, Sóc Trăng, Bạc Liêu, and Cà Mau, along with the province-level municipality of Cần Thơ.
The Mekong Delta Tours has been dubbed as a “biological treasure trove”. Over 1,000 animal species were recorded between 1997 and 2007 and new species of plants, fish, lizards, and mammals have been discovered in previously unexplored areas, including the Laotian rock rat, thought to be extinct.